Sortiert nach Autor

Publikationen - sortiert nach Autor

• Hoebart C, Rojas‐Galvan N, Ciotu C, Aykac I, Reissig L, Weninger W, Kiss A, Podesser B, Fischer M, Heber S (2021) No functional TRPA1 in cardiomyocytes Acta Physiol (Oxf)., 232 (4): e13659

• Gebhardt L, Kichko T, Fischer M, Reeh P (2020) TRPA1-dependent calcium transients and CGRP release in DRG neurons require extracellular calcium J Cell Biol, 219 (6)
• Ciotu C, Fischer M (2020) Novel Analgesics with Peripheral Targets Neurotherapeutics, 17 (3): 784-825
• Rodionova K, Veelken R, Hilgers K, Paulus E, Linz P, Fischer M, Schenker M, Reeh P, Tiegs G, Ott C, Schmieder R, Schiffer M, Amann K, Ditting T (2020) Afferent renal innervation in anti-Thy1.1 nephritis in rats Am J Physiol, 319 (5): F822-F832
• Kühn H, Kappes L, Wolf K, Gebhardt L, Neurath M, Reeh P, Fischer M, Kremer A (2020) Complementary roles of murine NaV1.7, NaV1.8 and NaV1.9 in acute itch signalling Sci Rep, 10 (1)
• Heber S, Ciotu C, Hartner G, Gold-Binder M, Ninidze N, Gleiss A, Kress H, Fischer M (2020) TRPV1 antagonist BCTC inhibits pH 6.0-induced pain in human skin Pain, 161 (7): 1532-1541

• Heber S, Fischer M (2019) Non-Analgesic Symptomatic or Disease—Modifying Potential of TRPA1 Med Sci (Basel), 7 (10): 99
• Meents J, Ciotu C, Fischer M (2019) TRPA1: a molecular view J. Neurophysiol., 121 (2): 427-443
• Heber S, Fischer B, Sallaberger-Lehner M, Hausharter M, Ocenasek H, Gleiss A, Fischer M, Pokan R, Assinger A, Volf I (2019) Effects of high-intensity interval training on platelet function in cardiac rehabilitation: a randomised controlled trial Heart, 106 (1): 69-79
• Schneider C, Gebhardt L, Arndt S, Karrer S, Zimmermann J, Fischer M, Bosserhoff A (2019) Acidification is an Essential Process of Cold Atmospheric Plasma and Promotes the Anti-Cancer Effect on Malignant Melanoma Cells Cancers, 11 (5): 671
• Aigner P, Mizutani T, Horvath J, Eder T, Heber S, Lind K, Just V, Moll H, Yeroslaviz A, Fischer M, Kenner L, Győrffy B, Sill H, Grebien F, Moriggl R, Casanova E, Stoiber D (2019) STAT3β is a tumor suppressor in acute myeloid leukemia Blood Adv., 3 (13): 1989-2002
• Babes A, Neacsu C, Fischer M, Messlinger K (2019) Sumatriptan activates TRPA1 Cephalalgia Reports, 2: 251581631984715
• Heber S, Gold-Binder M, Ciotu C, Witek M, Ninidze N, Kress H, Fischer M (2019) A Human TRPA1-Specific Pain Model J. Neurosci., 39 (20): 3845-3855
• Robering J, Gebhardt L, Wolf K, Kühn H, Kremer A, Fischer M (2019) Lysophosphatidic acid activates satellite glia cells and Schwann cells Glia, 67 (5): 999-1012

• Schneider C, Gebhardt L, Arndt S, Karrer S, Zimmermann JL, Fischer MJM, Bosserhoff AK (2018) Cold atmospheric plasma causes a calcium influx in melanoma cells triggering CAP-induced senescence Sci Rep, in press: in press
• Guenther F, Swozil F, Heber S, Buchfelder M, Messlinger K, Fischer MJ (2018) Pre- and postoperative headache in patients with meningioma Cephalalgia, in press: in press
• Fischer MJM, Schmidt J, Koulchitsky S, Klussmann S, Vater A, Messlinger K. (2018) Effect of a calcitonin gene-related peptide-binding L-RNA aptamer on neuronal activity in the rat spinal trigeminal nucleus J Headache Pain, 19(1): 3
• Meng J, Moriyama M, Feld M, Buddenkotte J, Buhl T, Szöllösi A, Zhang J, Miller P, Ghetti A, Fischer M, Reeh PW, Shan C, Wang J, Steinhoff M (2018) New mechanism underlying IL-31-induced atopic dermatitis J allergy clin Immun, 141(5): 1677-1689

• Dux M, Will C, Eberhardt M, Fischer MJM, Messlinger K. (2017) Stimulation of rat cranial dura mater with potassium chloride causes CGRP release into the cerebrospinal fluid and increases medullary blood flow Neuropeptides, 64: 61-68
• Babes A, Ciotu CI, Hoffmann T, Kichko TI, Selescu T, Neacsu C, Sauer SK, Reeh PW, Fischer MJM. (2017) Photosensitization of TRPA1 and TRPV1 by 7-dehydrocholesterol: implications for the Smith-Lemli-Opitz syndrome Pain, 158(12): 2475-2486
• Herrmann S, Rajab H, Christ I, Schirdewahn C, Höfler D, Fischer MJM, Bruno A, Fenske S, Gruner C, Kramer F, Wachsmann T, Wahl-Schott C, Stieber J, Biel M, Ludwig A. (2017) Protein kinase A regulates inflammatory pain sensitization by modulating HCN2 channel activity in nociceptive sensory neurons Pain, 158(10): 2012-2024
• Mack K, Fischer MJM (2017) Disrupting sensitization of TRPV4 BMC Neurosci, 352: 1-8
• Schwarz MG, Namer B, Reeh PW, Fischer MJM (2017) TRPA1 and TRPV1 Antagonists Do Not Inhibit Human Acidosis-Induced Pain J.Pain, 18(5): 526-534
• Meents JE, Fischer MJ, McNaughton PA (2017) Sensitization of TRPA1 by Protein Kinase A PLoS One, 12(1)

• Park J, Mazare A, Schneider H, von der Mark K, Fischer MJ, Schmuki P (2016) Electric Field-Induced Osteogenic Differentiation on TiO2 Nanotubular Layer Tissue Eng Part C Methods, 22(8): 809-21
• Bressan E, Touska F, Vetter I, Kistner K, Kichko TI, Teixeira NB, Picolo G, Cury Y, Lewis RJ, Fischer MJ, Zimmermann K, Reeh PW. (2016) Crotalphine desensitizes TRPA1 ion channels to alleviate inflammatory hyperalgesia Pain, 157(11): 2504-2516
• Meents JE, Fischer MJ, McNaughton PA (2016) Agonist-induced sensitisation of the irritant receptor ion channel TRPA1 J. Physiol., : 6643-6660
• Babes A, Sauer SK, Moparthi L, Kichko TI, Neacsu C, Namer B, Filipovic M, Zygmunt PM, Reeh PW, Fischer MJ. (2016) Photosensitization in Porphyrias and Photodynamic Therapy Involves TRPA1 and TRPV1 J. Neurosci., 36(19): 5264-78
• Rodionova K, Fiedler C, Guenther F, Grouzmann E, Neuhuber W, Fischer MJ, Ott C, Linz P, Freisinger W, Heinlein S, Schmidt ST, Schmieder RE, Amann K, Scrogin K, Veelken R, Ditting T. (2016) Complex reinnervation pattern after unilateral renal denervation in rats Am J Physiol, 310(9): R806-18
• Will C, Messlinger K, Fischer MJ. (2016) Vessel diameter measurements at the medullary brainstem in vivo as an index of trigeminal activity Brain Res, 1632: 51-57

• Wild V, Messlinger K, Fischer MJ. (2015) Hydrogen sulfide determines HNO-induced stimulation of trigeminal afferents. Neurosci Lett, 602: 104-9
• Fischer MJ, Soller KJ, Sauer SK, Kalucka J, Veglia G, Reeh PW. (2015) Formalin evokes calcium transients from the endoplasmatic reticulum PLoS One, 10(4): e0123762
• Emery EC, Diakogiannaki E, Gentry C, Psichas A, Habib AM, Bevan S, Fischer MJ, Reimann F, Gribble FM. (2015) Stimulation of glucagon-like peptide-1 secretion downstream of the ligand-gated ion channel TRPA1 Diabetes, 64(4): 1202-10

• Eberhardt M, Dux M, Namer B, Miljkovic J, Cordasic N, Will C, Kichko TI, de la Roche J, Fischer M, Suárez SA, Bikiel D, Dorsch K, Leffler A, Babes A, Lampert A, Lennerz JK, Jacobi J, Martí MA, Doctorovich F, Högestätt ED, Zygmunt PM, Ivanovic-Burmazovic I, Messlinger K, Reeh P, Filipovic MR (2014) H2S and NO cooperatively regulate vascular tone by activating a neuroendocrine HNO-TRPA1-CGRP signalling pathway Nat Commun, 5:4381
• Fischer MJ, Balasuriya D, Jeggle P, Goetze TA, McNaughton PA, Reeh PW, Edwardson JM. (2014) Direct evidence for functional TRPV1/TRPA1 heteromers European journal of physiology, 466(12): 2229-41
• Kageneck C, Nixdorf-Bergweiler BE, Messlinger K, Fischer MJ (2014) Release of CGRP from mouse brainstem slices indicates central inhibitory effect of triptans and kynurenate. J Headache Pain, 15:7
• Fischer M, Carli G, Raboisson P, Reeh P. (2014) The interphase of the formalin test J.Pain, 155(3): 511-21

• de la Roche J, Eberhardt MJ, Klinger AB, Stanslowsky N, Wegner F, Koppert W, Reeh PW, Lampert A, Fischer MJ, Leffler A. (2013) The molecular basis for species-specific activation of human TRPA1 protein by protons involves poorly conserved residues within transmembrane domains 5 and 6. J Biol chem, 288(28): 20280-92
• Hoffmann T, Kistner K, Miermeister F, Winkelmann R, Wittmann J, Fischer MJ, Weidner C, Reeh PW. (2013) TRPA1 and TRPV1 are differentially involved in heat nociception of mice Eur. J. Pain, 17(10): 1472-82
• Btesh J, Fischer MJM, Stott K, McNaughton PA. (2013) Mapping the binding site of TRPV1 on AKAP79: implications for inflammatory hyperalgesia. J. Neurosci., 22,33(21): 9184-9193
• Fischer MJ, Btesh J, McNaughton PA. (2013) Disrupting sensitization of transient receptor potential vanilloid subtype 1 inhibits inflammatory hyperalgesia. J. Neurosci., 33(17): 7407-14
• Babes A, Fischer MJ, Filipovic M, Engel MA, Flonta ML, Reeh PW. (2013) he anti-diabetic drug glibenclamide is an agonist of the transient receptor potential Ankyrin 1 (TRPA1) ion channel. Eur J Clin Pharmacol, 704(1-3): 15-22

• Eberhardt MJ, Filipovic MR, Leffler A, de la Roche J, Kistner K, Fischer MJ, Fleming T, Zimmermann K, Ivanovic-Burmazovic I, Nawroth PP, Bierhaus A, Reeh PW, Sauer SK. (2012) Methylglyoxal activates nociceptors through transient receptor potential channel A1 (TRPA1): a possible mechanism of metabolic neuropathies J Biol chem, 287(34): 28291-306
• Hammond GR1, Fischer MJ, Anderson KE, Holdich J, Koteci A, Balla T, Irvine RF (2012) PI4P and PI(4,5)P2 are essential but independent lipid determinants of membrane identity Science, 337(6095): 727-30
• Sisignano M, Park CK, Angioni C, Zhang DD, von Hehn C, Cobos EJ, Ghasemlou N, Xu ZZ, Kumaran V, Lu R, Grant A, Fischer MJ, Schmidtko A, Reeh P, Ji RR, Woolf CJ, Geisslinger G, Scholich K, Brenneis C. (2012) 5,6-EET is released upon neuronal activity and induces mechanical pain hypersensitivity via TRPA1 on central afferent terminals J. Neurosci., 32(18): 6364-72

• Brenneis C, Sisignano M, Coste O, Altenrath K, Fischer MJ, Angioni C, Fleming I, Brandes RP, Reeh PW, Woolf CJ, Geisslinger G, Scholich K. (2011) Soluble epoxide hydrolase limits mechanical hyperalgesia during inflammation Molecular Pain, : 7:78
• Dieterle A, Fischer MJ, Link AS, Neuhuber WL, Messlinger K. (2011) Increase in CGRP- and nNOS-immunoreactive neurons in the rat trigeminal ganglion after infusion of an NO donor. Cephalalgia, 31(1): 31-42
• Schmid D, Messlinger K, Belmonte C, Fischer MJ. (2011) Altered thermal sensitivity in neurons injured by infraorbital nerve lesion Neurosci Lett, 488(2): 168-72

• Fischer MJ, Leffler A, Niedermirtl F, Kistner K, Eberhardt M, Reeh PW, Nau C. (2010) The general anesthetic propofol excites nociceptors by activating TRPV1 and TRPA1 rather than GABAA receptors J Biol Chem, 285(45): 34781-92
• Fischer MJ, Uchida S, Messlinger K. (2010) Measurement of meningeal blood vessel diameter in vivo with a plug-in for ImageJ Microvasc Res, 80(2): 258-66
• Auer J, Reeh PW, Fischer MJ. (2010) Acid-induced CGRP release from the stomach does not depend on TRPV1 or ASIC3 Neurogastroenterol Motil, 22(6): 680-7

• Sixt ML, Messlinger K, Fischer MJ. (2009) Calcitonin gene-related peptide receptor antagonist olcegepant acts in the spinal trigeminal nucleus Brain, 132(11): 3134-41
• Eberhardt M, Neeb L, Vogel EM, Tiegs G, Reuter U, Messlinger K, Fischer MJ. (2009) Glyceroltrinitrate facilitates stimulated CGRP release but not gene expression of CGRP or its receptor components in rat trigeminal ganglia. Neuropeptides, 43 (6): 483-9
• Forster AB, Reeh PW, Messlinger K, Fischer MJ. (2009) High concentrations of morphine sensitize and activate mouse dorsal root ganglia via TRPV1 and TRPA1 receptors. Molecular Pain, 5 (17)
• Kroeger I, Erhardt A, Abt D, Fischer M, Biburger M, Rau T, Neuhuber WL, Tiegs G. (2009) The neuropeptide calcitonin gene-related peptide (CGRP) prevents inflammatory liver injury in mice. J Hepatol., 51(2): :342-53
• Schlechtweg PM, Röder J, Fischer MJ, Neuhuber W, Messlinger K. (2009) Increase in NADPH-diaphorase-positive and neuronal NO synthase immunoreactive neurons in the rat spinal trigeminal nucleus following infusion of a NO donor--evidence for a feed-forward process in NO production involved in trigeminal nociception Cephalalgia, 29(5): 566-79
• Koulchitsky S, Fischer MJ, Messlinger K. (2009) Calcitonin gene-related peptide receptor inhibition reduces neuronal activity induced by prolonged increase in nitric oxide in the rat spinal trigeminal nucleus Cephalalgia, 29(4): 408-17

• Eberhardt M, Hoffmann T, Sauer SK, Messlinger K, Reeh PW, Fischer MJ. (2008) Calcitonin gene-related peptide release from intact isolated dorsal root and trigeminal ganglia Neuropediatrics, 42 (3): 311-7
• Leffler A, Fischer MJ, Rehner D, Kienel S, Kistner K, Sauer SK, Gavva NR, Reeh PW, Nau C (2008) The vanilloid receptor TRPV1 is activated and sensitized by local anesthetics in rodent sensory neurons. J Clin Invest, 118 (2): 763-76
• Holom VH, Messlinger K, Fischer MJ. (2008) Temperature-dependent neuronal regulation of arterial blood flow in rat cranial dura mater J Neurosci, 86(1): 158-64

• Karl Meßlinger, R. De Col, T. Denekas, M. Dux, M. Eberhardt, S. V. Koulchitsky, J. Röder, P. M. Schlechtweg, M. L. Sixt, N. Schwenger, T. Strecker, M. Tröltzsch, M. J M Fischer (2007) Actions of nociceptive mediators in the trigeminovascular system as a basis for the generation of headaches Aktuelle Neurologie, 34(9): 504-507
• Paulini A, Fischer M, Rampp S, Scheler G, Hopfengärtner R, Kaltenhäuser M, Dörfler A, Buchfelder M, Stefan H. (2007) Lobar localization information in epilepsy patients: MEG--a useful tool in routine presurgical diagnosis. Epilepsia, 76(2-3: 124-130
• Agarwal N, Pacher P, Tegeder I, Amaya F, Constantin CE, Brenner GJ, Rubino T, Michalski CW, Marsicano G, Monory K, Mackie K, Marian C, Batkai S, Parolaro D, Fischer MJ, Reeh P, Kunos G, Kress M, Lutz B, Woolf CJ, Kuner R. (2007) Cannabinoids mediate analgesia largely via peripheral type 1 cannabinoid receptors in nociceptors. Nature Neurosci, 10(7): 870-9
• Fischer MJ, Reeh PW. (2007) Sensitization to heat through G-protein-coupled receptor pathways in the isolated sciatic mouse nerve. Eur J Neurosci, 25(12): 3570-5
• MJM Fischer, K Messlinger (2007) Cannabinoid and vanilloid effects of R(+)-methanandamide in the hemisected meningeal preparation. Cephalalgia, 27(5): 422-8
• Gabriela Scheler Michael J.M. Fischer Alexandra Genow Cornelia Hummel Stefan Rampp Andrea Paulini Rüdiger Hopfengärtner Martin Kaltenhäuser Hermann Stefan (2007) Spatial relationship of source localizations in patients with focal epilepsy: Comparison of MEG and EEG with a three spherical shells and a boundary element volume conductor model. Human Brain Mapping, 28 (4): 315-22

• Zimmermann K, Leffler A, Fischer MM, Messlinger K, Nau C, Reeh PW. (2005) The TRPV1/2/3 activator 2-aminoethoxydiphenyl borate sensitizes native nociceptive neurons to heat in wildtype but not TRPV1 deficient mice. J Neurosci, 135(4): 1277-1284
• Fischer MJ, Koulchitsky S, Messlinger K. (2005) The nonpeptide calcitonin gene-related peptide receptor antagonist BIBN4096BS lowers the activity of neurons with meningeal input in the rat spinal trigeminal nucleus. J. Neurosci., 25(25): 5877-5883

• Fischer MJ, Scheler G, Stefan H. (2004) Utilization of magnetoencephalography results to obtain favourable outcomes in epilepsy surgery. Brain, 128 (1): 153–157
• Stansilav Koulchitsky, Michael J.M. Fischer, Roberto De Col, Philipp M. Schlechtweg, and Karl Messlinger (2004) Biphasic response to nitric oxide of spinal trigeminal neurons with meningeal input in rat--possible implications for the pathophysiology of headaches. J. Neurophysiol., 92 (3): 1320-1328

• Fischer MJ, Reeh PW, Sauer SK (2003) Proton-induced calcitonin gene-related peptide release from rat sciatic nerve axons, in vitro, involving TRPV1. Eur. J. Neurosci., 18(4): 803-10

• Bernardini N, Sauer S, Haberberger R, Fischer M, Reeh P (2001) Excitatory Nicotinic and Desensitizing Muscarinic (M2) Effects on C-Nociceptors in Isolated Rat Skin J. Neurosci., 21 (9): 3295-3302