Sortiert nach Autor

Publikationen - sortiert nach Autor

• Muratspahić E, Tomašević N, Nasrollahi-Shirazi S, Gattringer J, Emser FS, Freissmuth M, Gruber CW (2021) Plant-Derived Cyclotides Modulate κ-Opioid Receptor Signaling. J Nat Prod, 84(8): 2238-2248
• Bhat S, Guthrie DA, Kasture A, El-Kasaby A, Cao J, Bonifazi A, Ku T, Giancola JB, Hummel T, Freissmuth M, Newman AH (2021) Tropane-based ibogaine analog rescues folding-deficient serotonin and dopamine transporters. ACS, 4: 503-516
• 191. Ng J, Barral S, De La Fuente Barrigon C, Lignani G, Erdem FA, Wallings R, Privolizzi R, Rossignoli G, Alrashidi H, Heasman S, Meyer E, Ngoh A, Pope S, Karda R, Perocheau D, Baruteau J, Suff N, Antinao Diaz J, Schorge S, Vowles J, Marshall LR, Cowley SA, Sucic S, Freissmuth M, Counsell J, Wade-Martins R, Heales SJR, Rahim AA, Bencze M, Waddington SN, Kurian MA (2021) Gene therapy restores dopamine transporter expression and ameliorates pathology in iPSC and mouse models of infantile parkinsonism. Sci Transl Med, 13(594): eaaw1564
• Esendir E, Burtscher V, Coleman JA, Zhu R, Gouaux E, Freissmuth M, Sandtner W (2021) Extracellular loops of the serotonin transporter act as a selectivity filter for drug binding J Biol Chem, 297(1): 00863
• Saha K, Yang J, Hofmaier T, Venkatesan S, Steinkellner T, Kudlacek O, Sucic S, Freissmuth M, Sitte H (2021) Constitutive Endocytosis of the Neuronal Glutamate Transporter Excitatory Amino Acid Transporter-3 Requires ARFGAP1 Front Physiol, 12
• Bhat S, Niello M, Schicker K, Pifl C, Sitte H, Freissmuth M, Sandtner W (2021) Handling of intracellular K+ determines voltage dependence of plasmalemmal monoamine transporter function eLife, 10
• Schicker K, Bhat S, Farr C, Burtscher V, Horner A, Freissmuth M, Sandtner W (2021) Descriptors of Secondary Active Transporter Function and How They Relate to Partial Reactions in the Transport Cycle Membran, 11 (3): 178

• Burtscher V, Hotka M, Freissmuth M, Sandtner W (2020) An electrophysiological approach to measure changes in the membrane surface potential in real time Biophys. J, 118(4): 813-825
• Nasrollahi-Shirazi S, Szöllösi D, Yang Q, Muratspahic E, El-Kasaby A, Sucic S, Stockner T, Nanoff C, Freissmuth M (2020) Functional impact of the G279S substitution in the adenosine A1-receptor (A1R-G279S), a mutation associated with Parkinson's disease Mol Pharmacol, 98: 250–266
• Farr C, El-Kasaby A, Freissmuth M, Sucic S (2020) The Creatine Transporter Unfolded: A Knotty Premise in the Cerebral Creatine Deficiency Syndrome Front.Synaptic Neuroscience, 12

• Sohail A, Jayaraman K, Venkatesan S, Gotfryd K, Daerr M, Gether U, Loland C, Wanner K, Freissmuth M, Sitte H, Sandtner W, Stockner T (2016) The Environment Shapes the Inner Vestibule of LeuT PloS Computational Biology, 12 (11): e1005197
• Mayer F, Luf A, Nagy C, Holy M, Schmid R, Freissmuth M, Sitte H (2016) Application of a Combined Approach to Identify New Psychoactive Street Drugs and Decipher Their Mechanisms at Monoamine Transporters Curr Top Behav Neurosci, : 2016 Dec 27. doi: 10.1007/7854_2016_63. [Epub ahead of print]

• Venkatesan S, Saha K, Sohail A, Sandtner W, Freissmuth M, Ecker G, Sitte H, Stockner T (2015) Refinement of the Central Steps of Substrate Transport by the Aspartate Transporter GltPh: Elucidating the Role of the Na2 Sodium Binding Site PloS Computational Biology, 11 (10): e1004551
• Li Y, Hasenhuetl P, Schicker K, Sitte H, Freissmuth M, Sandtner W (2015) Dual Action of Zn2+on the Transport Cycle of the Dopamine Transporter J Biol Chem, 290 (52): 31069-31076
• Zhu R, Sinwel D, Hasenhuetl P, Saha K, Kumar V, Zhang P, Rankl C, Holy M, Sucic S, Kudlacek O, Karner A, Sandtner W, Stockner T, Gruber H, Freissmuth M, Hauck Newman A, Sitte H, Hinterdorfer P (2015) Nanopharmacological Force Sensing to Reveal Allosteric Coupling in Transporter Binding Sites Angew Chem Int Ed, 55 (5): 1719-1722
• Kong E, Sucic S, Monje F, Reisinger S, Savalli G, Diao W, Khan D, Ronovsky M, Cabatic M, Koban F, Freissmuth M, Pollak D (2015) Corrigendum: STAT3 controls IL6-dependent regulation of serotonin transporter function and depression-like behaviour Sci Rep, 5: 11965
• Kong E, Sucic S, Monje F, Savalli G, Diao W, Khan D, Ronovsky M, Cabatic M, Koban F, Freissmuth M, Pollak D (2015) STAT3 controls IL6-dependent regulation of serotonin transporter function and depression-like behavior Sci Rep, 5: 9009

• Steinkellner T, Mus L, Eisenrauch B, Constantinescu A, Leo D, Konrad L, Rickhag M, Sørensen G, Efimova E, Kong E, Willeit M, Sotnikova T, Kudlacek O, Gether U, Freissmuth M, Pollak D, Gainetdinov R, Sitte H (2014) In vivo Amphetamine Action is Contingent on αCaMKII Neuropsychopharmacology, 39(11: :2681-2693
• Sandtner W, Schmid D, Schicker K, Gerstbrein K, Koenig X, Mayer F, Boehm S, Freissmuth M, Sitte H (2014) A quantitative model of amphetamine action on the 5-HT transporter Br J Pharmacol, 171 (4): 1007-1018
• Michl J, Scharinger C, Zauner M, Kasper S, Freissmuth M, Sitte H, Ecker G, Pezawas L (2014) A multivariate approach linking reported side effects of clinical antidepressant and antipsychotic trials to in vitro binding affinities Eur Neuropsychopharmacol, 24 (9): 1463-1474
  | Weblink |
• Scharinger C, Rabl U, Kasess C, Meyer B, Hofmaier T, Diers K, Bartova L, Pail G, Huf W, Uzelac Z, Hartinger B, Kalcher K, Perkmann T, Haslacher H, Meyer-Lindenberg A, Kasper S, Freissmuth M, Windischberger C, Willeit M, Lanzenberger R, Esterbauer H ,Brocke B, Moser E, Sitte H, Pezawas L (2014) Platelet Serotonin Transporter Function Predicts Default-Mode Network Activity PLoS One, 9 (3): e92543

• Montgomery T, Steinkellner T, Sucic S, Koban F, Schuchner S, Ogris E, Sitte H, Freissmuth M (2014) Axonal Targeting of the Serotonin Transporter in Cultured Rat Dorsal Raphe Neurons Is Specified by SEC24C-Dependent Export from the Endoplasmic Reticulum J Neurosci, 34 (18): 6344-6351
• Thurner P, Gsandtner I, Kudlacek O, Choquet D, Nanoff C, Freissmuth M, Zezula J (2014) A Two-state Model for the Diffusion of the A2A Adenosine Receptor in Hippocampal Neurons: AGONIST-INDUCED SWITCH TO SLOW MOBILITY IS MODIFIED BY SYNAPSE-ASSOCIATED PROTEIN 102 (SAP102) J Biol Chem, 289 (13): 9263-9274

• Bergmayr C, Thurner P, Keuerleber S, Kudlacek O, Nanoff C, Freissmuth M, Gruber C (2013) Recruitment of a Cytoplasmic Chaperone Relay by the A2A Adenosine Receptor J Biol Chem, 288 (40): 28831-28844
• Sucic S, Koban F, El-Kasaby A, Kudlacek O, Stockner T, Sitte H, Freissmuth M (2013) Switching the Clientele: A LYSINE RESIDING IN THE C TERMINUS OF THE SEROTONIN TRANSPORTER SPECIFIES ITS PREFERENCE FOR THE COAT PROTEIN COMPLEX II COMPONENT SEC24C J Biol Chem, 288 (8): 5330-5341

• Keuerleber S, Thurner P, Gruber C, Zezula J, Freissmuth M (2012) Reengineering the Collision Coupling and Diffusion Mode of the A2A-adenosine Receptor: PALMITOYLATION IN HELIX 8 RELIEVES CONFINEMENT J Biol Chem, 287 (50): 42104-42118

• Rabl U, Scharinger C, Hofmaier T, Freissmuth M, Pezawas L (2011) Genetic Regulation of Emotion Brain Circuitries. In: , Frontiers in Neuroscience : 75-96

• Sucic S, Dallinger S, Zdrazil B, Weissensteiner R, Jorgensen T, Holy M, Kudlacek O, Seidel S, Cha J, Gether U, Newman A, Ecker G, Freissmuth M, Sitte H (2010) The N Terminus of Monoamine Transporters Is a Lever Required for the Action of Amphetamines J Biol Chem, 285 (14): 10924-10938

• Steiner I, Errhalt P, Kubesch K, Hubner M, Holy M, Bauer M, Müller M, Hinterberger S, Widmann R, Mascher D, Freissmuth M, Kneussl M (2008) Pulmonary pharmacokinetics and safety of nebulized duramycin in healthy male volunteers Naunyn Schmiedebergs Arch Pharmacol, 378 (3): 323-333

• Stefan Seidel, Ernst A. Singer, Herwig Just, Hesso Farhan, Petra Scholze, Oliver Kudlacek, Marion Holy, Karl Koppatz, Peter Krivanek, Michael Freissmuth, and Harald H. Sitte (2005) Amphetamines Take Two to Tango: an Oligomer-Based Counter-Transport Model of Neurotransmitter Transport Explores the Amphetamine Action Mol Pharmacol, 67: 140-151

• Scholze P, Freissmuth M, Sitte H (2002) Mutations within an Intramembrane Leucine Heptad Repeat Disrupt Oligomer Formation of the Rat GABA Transporter 1 J Biol Chem, 277 (46): 43682-43690
  | Article (PDF) |

• Schmid J, Scholze P, Kudlacek O, Freissmuth M, Singer E, Sitte H (2001) Oligomerization of the Human Serotonin Transporter and of the Rat GABA Transporter 1 Visualized by Fluorescence Resonance Energy Transfer Microscopy in Living Cells J Biol Chem, 276 (6): 3805-3810
  | Article (PDF) |

• O'Connor V, El Far O, Bofill-Cardona E, Nanoff C, Freissmuth M, Karschin A, Airas JM, Betz H, Boehm S. (1999) Calmodulin dependence of presynaptic metabotropic glutamate receptor signaling Science, 286: 1180-1184