Sortiert nach PI

Publikationen - sortiert nach Principle Investigator

• Sauerzopf U, Weidenauer A Praschak-Rieder N, Kasper S Sitte H, Willeit M (2018) Reprogrammierte Zellen: Zukunft der psychiatrischen Forschung? Journal für Neurologie, Neurochirurgie und Psychiatrie, 19 (2): 60-63
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• Anderluh A, Hofmaier T, Klotzsch E, Kudlacek O, Stockner T, Sitte H, Schütz G (2017) Direct PIP2 binding mediates stable oligomer formation of the serotonin transporter Nat Commun, 8: 14089

• Weidenauer A, Bauer M, Sauerzopf U, Bartova L, Praschak-Rieder N, Sitte H, Kasper S, Willeit M (2017) Making Sense of: Sensitization in Schizophrenia Int J Neuropsychopharmacol, 20 (1): 1-10
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• McLaughlin G, Morris N, Kavanagh P, Dowling G, Power J, Twamley B, O'Brien J, Talbot B, Sitte H, Brandt S (2016) Test purchase, synthesis and characterization of 3-fluorophenmetrazine (3-FPM) and differentiation from its ortho- and para-substituted isomers Drug Test Anal, 9 (3): 369-377
• Mayer F, Wimmer L, Dillon-Carter O, Partilla J, Burchardt N, Mihovilovic M, Baumann M, Sitte H (2016) Phase I metabolites of mephedrone display biological activity as substrates at monoamine transporters Br J Pharmacol, 173 (17): 2657-2668
• Sauerzopf U, Sacco R, Novarino G, Niello M, Weidenauer A, Praschak-Rieder N, Sitte H, Willeit M (2016) Are reprogrammed cells a useful tool for studying dopamine dysfunction in psychotic disorders? A review of the current evidence Eur J Neurosci, 45 (1): 45-57
• Sohail A, Jayaraman K, Venkatesan S, Gotfryd K, Daerr M, Gether U, Loland C, Wanner K, Freissmuth M, Sitte H, Sandtner W, Stockner T (2016) The Environment Shapes the Inner Vestibule of LeuT PloS Computational Biology, 12 (11): e1005197
• Seddik A, Geerke D, Stockner T, Holy M, Kudlacek O, Cozzi N, Ruoho A, Sitte H, Ecker G (2016) Combined Simulation and Mutation Studies to Elucidate Selectivity of Unsubstituted Amphetamine-like Cathinones at the Dopamine Transporter Mol Inform, 36 (5-6): 1600094
• Sweeney C, Tremblay B, Stockner T, Sitte H, Melikian H (2016) Dopamine Transporter Amino and Carboxyl Termini Synergistically Contribute to Substrate and Inhibitor Affinities J Biol Chem, 292 (4): 1302-1309
• Mayer F, Luf A, Nagy C, Holy M, Schmid R, Freissmuth M, Sitte H (2016) Application of a Combined Approach to Identify New Psychoactive Street Drugs and Decipher Their Mechanisms at Monoamine Transporters Curr Top Behav Neurosci, : 2016 Dec 27. doi: 10.1007/7854_2016_63. [Epub ahead of print]
• Billesbølle C, Mortensen J, Sohail A, Schmidt S, Shi L, Sitte H, Gether U, Loland C (2016) Transition metal ion FRET uncovers K+ regulation of a neurotransmitter/sodium symporter Nat Commun, 7: 12755
• Sitte HH, Pifl C, Rajput AH, Hörtnagl H, Tong J, Lloyd GK, Kish SJ, Hornykiewicz O (2016) Dopamine and noradrenaline, but not serotonin, in the human claustrum are greatly reduced in patients with Parkinson's disease: possible functional implications Eur J Neurosci, 45: 192-197
• Wiedermann U, Sitte HH, Burgmann H, Eser A, Falb P, Holzmann H, Kitchen M, Köller M, Kollaritsch H, Kundi M, Lassmann H, Mutz I, Pickl WF, Riedl E, Sibilia M, Thalhammer F, Tucek B, Zenz W, Zwiauer K. (2016) Guidelines for vaccination of immunocompromised individuals Wiener Klinische Wochenschrift, 128 (S4): 337-376
• Meyer B, Huemer J, Rabl U, Boubela R, Kalcher K, Berger A, Banaschewski T, Barker G, Bokde A, Büchel C, Conrod P, Desrivières S, Flor H, Frouin V, Gallinat J, Garavan H, Heinz A, Ittermann B, Jia T, Lathrop M, Martinot J, Nees F, Rietschel M, Smolka M, Bartova L, Popovic A, Scharinger C, Sitte H, Steiner H, Friedrich M, Kasper S, Perkmann T, Praschak-Rieder N, Haslacher H, Esterbauer H, Moser E, Schumann G, Pezawas L (2016) Oppositional COMT Val158Met effects on resting state functional connectivity in adolescents and adults Brain Struct Funct, 221 (1): 103-114
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• Venkatesan S, Saha K, Sohail A, Sandtner W, Freissmuth M, Ecker G, Sitte H, Stockner T (2015) Refinement of the Central Steps of Substrate Transport by the Aspartate Transporter GltPh: Elucidating the Role of the Na2 Sodium Binding Site PloS Computational Biology, 11 (10): e1004551
• Li Y, Hasenhuetl P, Schicker K, Sitte H, Freissmuth M, Sandtner W (2015) Dual Action of Zn2+on the Transport Cycle of the Dopamine Transporter J Biol Chem, 290 (52): 31069-31076
• Zhu R, Sinwel D, Hasenhuetl P, Saha K, Kumar V, Zhang P, Rankl C, Holy M, Sucic S, Kudlacek O, Karner A, Sandtner W, Stockner T, Gruber H, Freissmuth M, Hauck Newman A, Sitte H, Hinterdorfer P (2015) Nanopharmacological Force Sensing to Reveal Allosteric Coupling in Transporter Binding Sites Angew Chem Int Ed, 55 (5): 1719-1722
• Sandtner W, Stockner T, Hasenhuetl P, Partilla J, Seddik A, Zhang Y, Cao J, Holy M, Steinkellner T, Rudnick G, Baumann M, Ecker G, Newman A, Sitte H (2015) Binding Mode Selection Determines the Action of Ecstasy Homologs at Monoamine Transporters Mol Pharmacol, 89 (1): 165-175
• Bartova L, Meyer B, Diers K, Rabl U, Scharinger C, Popovic A, Pail G, Kalcher K, Boubela R, Huemer J, Mandorfer D, Windischberger C, Sitte H, Kasper S, Praschak-Rieder N, Moser E, Brocke B, Pezawas L (2015) Reduced Default Mode Network Suppression during a Working Memory Task in Remitted Major Depression J Psychiatr Res, 64: 9-18

• Steinkellner T, Mus L, Eisenrauch B, Constantinescu A, Leo D, Konrad L, Rickhag M, Sørensen G, Efimova E, Kong E, Willeit M, Sotnikova T, Kudlacek O, Gether U, Freissmuth M, Pollak D, Gainetdinov R, Sitte H (2014) In vivo Amphetamine Action is Contingent on αCaMKII Neuropsychopharmacology, 39(11: :2681-2693
• Romanov R, Alpar A, Zhang M, Zeisel A, Calas A, Landry M, Fuszard M, Shirran SL, Schnell R, Dobolyi A, Olah M, Spence L, Mulder J, Martens H, Palkovits M, Uhlen M, Sitte H, Botting CH, Wagner L, Linnarsson S, Hökfelt T, Harkany T (2014) A secretagonin locus of the mammalian hypothalamus controls stress hormon release EMBO J., 34 (1): 36-54
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• Meyer BM, Huemer J, Rabl U, Boubela RN, Kalcher K, Berger A, Banaschewski T, Barker G, Bokde A, Büchel C, Conrod P, Desrivières S, Flor H, Frouin V, Gallinat J, Garavan H, Heinz A, Ittermann B, Jia T, Lathrop M, Martinot JL, Nees F, Rietschel M, Smolka MN, Bartova L, Popovic A, Scharinger C, Sitte HH, Steiner H, Friedrich MH, Kasper S, Perkmann T, Praschak-Rieder N, Haslacher H, Esterbauer H, Moser E, Schumann G, Pezawas L (2014) Oppositional COMT Val158Met effects on resting state functional connectivity in adolescents and adults Brain Struct Funct, 221(1): 103-114
• Sandtner W, Schmid D, Schicker K, Gerstbrein K, Koenig X, Mayer F, Boehm S, Freissmuth M, Sitte H (2014) A quantitative model of amphetamine action on the 5-HT transporter Br J Pharmacol, 171 (4): 1007-1018
• Kivell B, Uzelac Z, Sundaramurthy S, Rajamanickam J, Ewald A, Chefer V, Jaligam V, Bolan E, Simonson B, Annamalai B, Mannangatti P, Prisinzano T, Gomes I, Devi L, Jayanthi L, Sitte H, Ramamoorthy S, Shippenberg T (2014) Salvinorin A regulates dopamine transporter function via a kappa opioid receptor and ERK1/2-dependent mechanism Neuropharmacology, 86: 228-240
• Rabl U, Meyer B, Diers K, Bartova L, Berger A, Mandorfer D, Popovic A, Scharinger C, Huemer J, Kalcher K, Pail G, Haslacher H, Perkmann T, Windischberger C, Brocke B, Sitte H, Pollak D, Dreher J, Kasper S, Praschak-Rieder N, Moser E, Esterbauer H, Pezawas (2014) Additive Gene-Environment Effects on Hippocampal Structure in Healthy Humans J Neurosci, 34 (30): 9917-9926
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• Michl J, Scharinger C, Zauner M, Kasper S, Freissmuth M, Sitte H, Ecker G, Pezawas L (2014) A multivariate approach linking reported side effects of clinical antidepressant and antipsychotic trials to in vitro binding affinities Eur Neuropsychopharmacol, 24 (9): 1463-1474
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• Scharinger C, Rabl U, Kasess C, Meyer B, Hofmaier T, Diers K, Bartova L, Pail G, Huf W, Uzelac Z, Hartinger B, Kalcher K, Perkmann T, Haslacher H, Meyer-Lindenberg A, Kasper S, Freissmuth M, Windischberger C, Willeit M, Lanzenberger R, Esterbauer H ,Brocke B, Moser E, Sitte H, Pezawas L (2014) Platelet Serotonin Transporter Function Predicts Default-Mode Network Activity PLoS One, 9 (3): e92543

• Montgomery T, Steinkellner T, Sucic S, Koban F, Schuchner S, Ogris E, Sitte H, Freissmuth M (2014) Axonal Targeting of the Serotonin Transporter in Cultured Rat Dorsal Raphe Neurons Is Specified by SEC24C-Dependent Export from the Endoplasmic Reticulum J Neurosci, 34 (18): 6344-6351

• Buchmayer F, Schicker K, Steinkellner T, Geier P, Stubiger G, Hamilton P, Jurik A, Stockner T, Yang J, Montgomery T, Holy M, Hofmaier T, Kudlacek O, Matthies H, Ecker G, Bochkov V, Galli A, Boehm S, Sitte H (2013) Amphetamine actions at the serotonin transporter rely on the availability of phosphatidylinositol-4,5-bisphosphate PNAS, 110 (28): 11642-11647

• Sucic S, Koban F, El-Kasaby A, Kudlacek O, Stockner T, Sitte H, Freissmuth M (2013) Switching the Clientele: A LYSINE RESIDING IN THE C TERMINUS OF THE SEROTONIN TRANSPORTER SPECIFIES ITS PREFERENCE FOR THE COAT PROTEIN COMPLEX II COMPONENT SEC24C J Biol Chem, 288 (8): 5330-5341

• Sucic S, Dallinger S, Zdrazil B, Weissensteiner R, Jorgensen T, Holy M, Kudlacek O, Seidel S, Cha J, Gether U, Newman A, Ecker G, Freissmuth M, Sitte H (2010) The N Terminus of Monoamine Transporters Is a Lever Required for the Action of Amphetamines J Biol Chem, 285 (14): 10924-10938

• Scharinger C, Rabl U, Sitte H, Pezawas L (2010) Imaging genetics of mood disorders Neuroimage, 53 (3): 810-821

• Willeit M, Sitte H, Thierry N, Michalek K, Praschak-Rieder N, Zill P, Winkler D, Brannath W, Fischer M, Bondy B, Kasper S, Singer E (2008) Enhanced Serotonin Transporter Function during Depression in Seasonal Affective Disorder Neuropsychopharmacology, 33 (7): 1503-1513
• Maier S., Reiterer V., Ruggiero A.M., Rothstein J.D., Thomas S., Dahm R., Sitte H.H., Farhan H. (2008) GTRAP3-18 serves as a negative regulator of Rab1 in protein transport and neuronal differentiation J Cell Mol Med, 13: 114-24
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• Rajput A.H., Sitte H.H., Rajput A., Fenton M.E., Pifl C., Hornykiewicz O. (2008) Globus pallidus dopamine and Parkinson motor subtypes. Neurology, 70: 1403-1410
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• Stefan Seidel, Ernst A. Singer, Herwig Just, Hesso Farhan, Petra Scholze, Oliver Kudlacek, Marion Holy, Karl Koppatz, Peter Krivanek, Michael Freissmuth, and Harald H. Sitte (2005) Amphetamines Take Two to Tango: an Oligomer-Based Counter-Transport Model of Neurotransmitter Transport Explores the Amphetamine Action Mol Pharmacol, 67: 140-151
• Seidel S, Singer EA, Just H, Farhan H, Scholze P, Kudlacek O, Holy M, Koppatz K, Krivanek P, Freissmuth M, Sitte HH (2005) Amphetamines take two to tango: an oligomer-based counter-transport model of neurotransmitter transport explores the amphetamine action Mol Pharmacol, 67: 140-151
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• Hilber B, Scholze P, Dorostkar MM, Sandtner W, Holy M, Boehm S, Singer EA, Sitte HH (2005) Serotonin-transporter mediated efflux: a pharmacological analysis of amphetamines an non-amphetamines Neuropharmacology, 49: 811-819
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• Farhan H, Korkhov VM, Paulitschke V, Dorostkar MM, Scholze P, Kudlacek O, Freissmuth M, Sitte HH (2004) Two discontinuous segments in the carboxyl terminus are required for membrane targeting of the rat gamma-aminobutyric acid transporter-1 (GAT1) J Biol Chem, 279: 28553-28563
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• Rajput AH, Fenton ME , Di Paolo T, Sitte H, Pifl C Hornykiewicz O (2004) Human brain dopamine metabolism in levodopa-induced dyskinesia and wearing-off Parkinsonism & Related Disorders, 10: 221-226

• Scholze P, Freissmuth M, Sitte H (2002) Mutations within an Intramembrane Leucine Heptad Repeat Disrupt Oligomer Formation of the Rat GABA Transporter 1 J Biol Chem, 277 (46): 43682-43690
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• Sitte H, Singer E, Scholze P (2002) Bi-directional transport of GABA in human embryonic kidney (HEK-293) cells stably expressing the rat GABA transporter GAT-1 Br J Pharmacol, 135 (1): 93-102
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• Scholze P, Sitte H, Singer E (2001) Substantial loss of substrate by diffusion during uptake in HEK-293 cells expressing neurotransmitter transporters Neurosci Lett, 309 (3): 173-176
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• Schmid J, Scholze P, Kudlacek O, Freissmuth M, Singer E, Sitte H (2001) Oligomerization of the Human Serotonin Transporter and of the Rat GABA Transporter 1 Visualized by Fluorescence Resonance Energy Transfer Microscopy in Living Cells J Biol Chem, 276 (6): 3805-3810
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• Sitte H.H., Wanschitz J., Budka H., Berger M.L. (2001) Autoradiography with [3H]PK11195 of spinal tract degeneration in amyotrophic lateral sclerosis Acta Neuropathol, 101: 75-78
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• Sitte HH, Hiptmair B, Zwach J, Pifl C, Singer EA, Scholze P (2001) Quantitative analysis of inward and outward transport rates in cells stably expressing the cloned human serotonin transporter: inconsistencies with the hypothesis of facilitated exchange diffusion Mol Pharmacol, 59: 1129-1137
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• Pifl C, Sitte HH, Reither H, Singer EA (2000) The mechanism of the releasing action of amphetamine. Uptake, superfusion and electrophysiological studies on transporter-transfected cells Pure Appl Chem, 72: 1045-1050
• Sitte HH, Scholze P, Schloss P, Pifl C, Singer EA (2000) Characterization of carrier-mediated efflux in human embryonic kidney 293 cells stably expressing the rat serotonin transporter: a superfusion study J Neurochem, 74: 1317-1324
• Scholze P, Zwach J, Kattinger A, Pifl V, Singer EA, Sitte HH (2000) Transporter-mediated release: a superfusion study on human embryonic kidney cells stably expressing the human serotonin transporter J Pharmacol Exp Ther, 293: 870-878p

• Pifl C, Agneter E, Drobny H, Sitte HH, Singer EA (1999) Amphetamine reverses or blocks the operation of the human noradrenaline transporter depending on its concentration: superfusion studies on transfected cells Neuropharmacology, 38: 157-165

• Sitte HH, Huck S, Reither H, Boehm S, Singer EA, Pifl C (1998) Carrier-mediated release, transport rates and charge transfer induced by amphetamine, tyramine and dopamine in mammalian cells transfected with the human dopamine transporter J Neurochem, 71: 1289-1297