Sortiert nach PI

Publikationen - sortiert nach Principle Investigator

• Görgülü I, Jagannath V, Pons S, Koniuszewski F, Groszer M, Maskos U, Huck S, Scholze P (2024) The human‐specific nicotinic receptor subunit CHRFAM7A reduces α7 receptor function in human induced pluripotent stem cells‐derived and transgenic mouse neurons Eur J Neurosci, 60 (5): 4893-4906
• Müller V, Ernst M, Baykuchkarova A, Koniuszewski F, Bampali K, Seidel T, Scholze P (2024) Probes for the heterogeneity of muscimol binding sites in rat brain Front. Pharmacol., 15
• Huber A, Sarne V, Beribisky A, Ackerbauer D, Derdak S, Madritsch S, Etzler J, Huck S, Scholze P, Gorgulu I, Christodoulou J, Studenik C, Neuhaus W, Connor B, Laccone F, Steinkellner H (2024) Generation and Characterization of a Human Neuronal In Vitro Model for Rett Syndrome Using a Direct Reprogramming Method Stem Cells Dev, 33 (5-6): 128-142
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• Sharmin D, Divović B, Ping X, Cerne R, Smith J, Rezvanian S, Mondal P, Meyer M, Kiley M, Arnold L, Mian M, Pandey K, Jin X, Mitrović J, Djorović D, Lippa A, Cook J, Golani L, Scholze P, Savić M, Witkin J (2024) New Imidazodiazepine Analogue, 5-(8-Bromo-6-(pyridin-2-yl)-4H-benzo-f-imidazo[1,5-a][1,4]diazepin-3-yl)oxazole, Provides a Simplified Synthetic Scheme, High Oral Plasma and Brain Exposures, and Produces Antiseizure Efficacy in Mice, and Antiepileptogenic Activity in Neural Networks in Brain Slices from a Patient with Mesial Temporal Lobe Epilepsy ACS Chem Neurosci, 15 (3): 517-526
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• Milica Gajić Bojić, Marco Treven, Kamal P. Pandey, V.V.N. Phani Babu Tiruveedhula, Anja Santrač, Đorđe Đukanović , Nataša Vojinović, Ljiljana Amidžić,Ranko Škrbić, Petra Scholze, Margot Ernst, James M. Cook,Miroslav M. Savić (2023) Vascular effects of midazolam, flumazenil, and a novel imidazobenzodiazepine MP-III-058 on isolated rat aorta Can.J.Physiol.Pharmacol.,
• Arias H, De Deurwaerdère P, Scholze P, Sakamoto S, Hamachi I, Di Giovanni G, Chagraoui A (2023) Coronaridine congeners induce sedative and anxiolytic-like activity in naïve and stressed/anxious mice by allosteric mechanisms involving increased GABAA receptor affinity for GABA Eur J Pharmacol, 953: 175854

• Simeone X, Ernst M, Seidel T, Heider J, Enz D, Monticelli S, Vogel F, Koniuszewski F, Langer T, Scholze P, Pace V, Miele M (2022) Novel alpha6 preferring GABA-A receptor ligands based on loreclezole Bioorg Med Chem, 244: 114780
• Goisis R, Chiavegato A, Gomez-Gonzalo M, Marcon I, Requie L, Scholze P, Carmignoto G, Losi G (2022) GABA tonic currents and glial cells are altered during epileptogenesis in a mouse model of Dravet syndrome Front Cell Neurosci, 16

• Simeone X, Koniuszewski F, Müllegger M, Smetka A, Steudle F, Puthenkalam R, Ernst M, Scholze P (2021) A Benzodiazepine Ligand with Improved GABAA Receptor α5-Subunit Selectivity Driven by Interactions with Loop C Mol Pharmacol, 99 (1): 39-48

• Scholze P, Huck S (2020) The α5 Nicotinic Acetylcholine Receptor Subunit Differentially Modulates α4β2* and α3β4* Receptors Front.Synaptic Neuroscience, 12
• Sharp B, Jiang Q, Simeone X, Scholze P (2020) Allosteric Modulation of GABAA Receptors in Rat Basolateral Amygdala Blocks Stress-Enhanced Reacquisition of Nicotine Self-Administration ACS, 3 (6): 1158-1164
• Perniss A, Latz A, Boseva I, Papadakis T, Dames C, Meisel C, Meisel A, Scholze P, Kummer W, Krasteva-Christ G (2020) Acute nicotine administration stimulates ciliary activity via α3β4 nAChR in the mouse trachea Int. Immunopharmacol., 84: 106496
• Tsymala I, Nigritinou M, Zeka B, Schulz R, Niederschick F, Matković M, Bauer I, Szalay M, Schanda K, Lerch M, Misu T, Fujihara K, Bennett J, Dahle C, Pache F, Rommer P, Leutmezer F, Illes Z, Leite M, Palace J, Scholze P, Reindl M, Lassmann H, Bradl M (2020) Induction of aquaporin 4-reactive antibodies in Lewis rats immunized with aquaporin 4 mimotopes Acta Neuropathologica Communications, 15; 8 (1)
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• Arias H, Do Rego J, Do Rego J, Chen Z, Anouar Y, Scholze P, Gonzales E, Huang R, Chagraoui A (2020) Coronaridine congeners potentiate GABAA receptors and induce sedative activity in mice in a benzodiazepine-insensitive manner Prog Neuropsychopharmacol Biol Psychiatry, 101: 109930
• Iorio M, Vogel F, Koniuszewski F, Scholze P, Rehman S, Simeone X, Schnürch M, Mihovilovic M, Ernst M (2020) GABAA Receptor Ligands Often Interact with Binding Sites in the Transmembrane Domain and in the Extracellular Domain—Can the Promiscuity Code Be Cracked? Int J Mol Sci, 21 (1): 334