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Medical NeuroScience Cluster Publications by Ernst, Margot

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2023 Original Articles

  • Milica Gajić Bojić, Marco Treven, Kamal P. Pandey, V.V.N. Phani Babu Tiruveedhula, Anja Santrač, Đorđe Đukanović , Nataša Vojinović, Ljiljana Amidžić,Ranko Škrbić, Petra Scholze, Margot Ernst, James M. Cook,Miroslav M. Savić (2023) Vascular effects of midazolam, flumazenil, and a novel imidazobenzodiazepine MP-III-058 on isolated rat aorta Can.J.Physiol.Pharmacol.,
  • Koniuszewski F, Vogel F, Dajić I, Seidel T, Kunze M, Willeit M, Ernst M (2023) Navigating the complex landscape of benzodiazepine- and Z-drug diversity: insights from comprehensive FDA adverse event reporting system analysis and beyond Front Psychiatry, 14
  • Mortensen M, Xu Y, Shehata M, Krall J, Ernst M, Frølund B, Smart T (2023) Pregnenolone sulfate analogues differentially modulate GABA<sub>A</sub> receptor closed/desensitised states Br J Pharmacol,
  • Bampali K, Koniuszewski F, Vogel F, Fabjan J, Andronis C, Lekka E, Virvillis V, Seidel T, Delaunois A, Royer L, Rolf M, Giuliano C, Traebert M, Roussignol G, Fric-Bordat M, Mazelin-Winum L, Bryant S, Langer T, Ernst M (2023) GABAA receptor-mediated seizure liabilities: a mixed-methods screening approach JCB,

2022 Original Articles

  • Schmiedhofer P, Vogel F, Koniuszewski F, Ernst M (2022) Cys-loop receptors on cannabinoids: All high? Front Physiol, 13
  • Garifulina A, Friesacher T, Stadler M, Zangerl-Plessl E, Ernst M, Stary-Weinzinger A, Willam A, Hering S (2022) β subunits of GABAA receptors form proton-gated chloride channels: Insights into the molecular basis Commun Biol, 5 (1)
  • Simeone X, Ernst M, Seidel T, Heider J, Enz D, Monticelli S, Vogel F, Koniuszewski F, Langer T, Scholze P, Pace V, Miele M (2022) Novel alpha6 preferring GABA-A receptor ligands based on loreclezole Bioorg Med Chem, 244: 114780
  • Koniuszewski F, Vogel F, Bampali K, Fabjan J, Seidel T, Scholze P, Schmiedhofer P, Langer T, Ernst M (2022) Molecular Mingling: Multimodal Predictions of Ligand Promiscuity in Pentameric Ligand-Gated Ion Channels MB, 9
  • Bampali K, Koniuszewski F, Silva L, Rehman S, Vogel F, Seidel T, Scholze P, Zirpel F, Garon A, Langer T, Willeit M, Ernst M (2022) Tricyclic antipsychotics and antidepressants can inhibit α5‐containing GABA <sub>A</sub> receptors by two distinct mechanisms Br J Pharmacol, 0: 1-18
  • Vogel F, Krenn M, Westphal D, Graf E, Wagner M, Leiz S, Koniuszewski F, Augé‐Stock M, Kramer G, Scholze P, Ernst M (2022) A de novo missense variant in GABRA4 alters receptor function in an epileptic and neurodevelopmental phenotype Epilepsia, 0: 1-7

2022 Reviews

  • Sieghart W, Chiou LC, Ernst M, Fabjan J, M Savić M, Lee MT (2022) α6-Containing GABAA Receptors: Functional Roles and Therapeutic Potentials Pharmacol Rev, 74(1): 238-270

2021 Original Articles

  • Fabjan J, Koniuszewski F, Schaar B, Ernst M (2021) Structure-Guided Computational Methods Predict Multiple Distinct Binding Modes for Pyrazoloquinolinones in GABAA Receptors Front Neurosci, 14: 611953
  • Simeone X, Koniuszewski F, Müllegger M, Smetka A, Steudle F, Puthenkalam R, Ernst M, Scholze P (2021) A Benzodiazepine Ligand with Improved GABAA Receptor α5-Subunit Selectivity Driven by Interactions with Loop C Mol Pharmacol, 99 (1): 39-48